COBRA Meetings
mini cobra course in richland, wa. April 30th - May 1st
***March 9th: The course is at capacity. If you belong to one of the Centers or have been in contact with the organizers or affiliated NIH Program Officers, please inquire about taking one of the reserved slots. Please e-mail mini.cobra.course at gmail.com to receive e-mail notification for future course***
***Feb. 29th: The course is near capacity. Please e-mail mini.cobra.course at gmail.com to check availability or to receive e-mail notification for future course***
Mini-COBRA: Constraints-based modeling of metabolism for beginners and
biologists – April 30th-May 1st in Richland, WA
In league with the Center for Systems Biology of Enteropathogens (funded by NIH/NIAID), we’re going to offer a two day mini course covering aspects of constraints-based modeling. This two-day course will be held from April 30th through May 1st at the Center’s head–Pacific Northwest National Laboratory–in Richland, Washington. If you’re interested in attending please enquire at mini.cobra.course at gmail.com.
We’ll have limited slots available for attendees that are not associated with NIAID’s Centers for Systems Biology. In the e-mail, please provide your affiliations and level of experience with computer modeling and biology. This course is targeted towards beginners and biologists thus an advanced student should consider attending the annual short course that’s held in Iceland during the summer.
There is no registration fee and we will not provide meals, housing, computers, refreshments, ponies, snakes, or motorcars to attendees.
Please note that potential attendees will have to complete security clearance paperwork with PNNL which can take 4-6 weeks for foreign nationals.
Nearby hotels are listed below (none of which are explicitly endorsed by the openCOBRA Project or the Center) with option 1, Guest House–PNNL, being closest. It might be a good idea to consider a rental car (and d.d.) because Richland’s in The Heart of Washington Wine Country®.
Day 1:
Morning (2.5 hours):
Introduction to mass-balanced modeling of metabolism.
Solving a system of simple biochemical equations with linear algebra.
Genome-scale models of metabolism.
Simulating biological objectives with flux balance analysis.
Afternoon (2.5 hours):
Installation and introduction to software.
Constructing a simple chemical model and simulating maximum yield.
Genome-Scale Models: Importing, editing models and growth
media, and identifying essential genes or reactions.
Day 2:
Morning (2.5 hours):
Protocol for constructing a genome-scale model of metabolism.
Comparing simulations through flux variability analysis and sampling.
Analysis of omics data with genome-scale models of metabolism.
Afternoon (2.5 hours):
Identifying gaps in a model and candidates to fill these gaps.
Comparing simulations for growth in two distinct media or WT vs mutants.
Identification of reporter metabolites.
Creation of condition-specific models and identification of
differences in metabolic activities.
Nearby Hotels
LIST OF HOTELS IN RICHLAND, WA
Name of Hotel
Address
Contact Details
Number of Miles to PNNL
1.Guest House – PNNL
Please visit the PNNL website at www.pnl.gov/guesthouse for more information.
620 Battelle Boulevard
Richland, WA 99352
The Guest House is within easy walking distance of most PNNL research facilities.
Amy Stephens
Guest Services Manager
amy@paragoncorporatehousing.com
Phone No.: 509.943.0500
Fax No.: 509.375.1092
.17 miles or 31 seconds
2. Clarion Hotel & Conference Center
http://www.clarionhotel.com/?promo=mncr032
1515 George Washington Way
Richland, WA 99354
Phone No.: 509.946.4121
Fax No.: 509.946.2222
3.89 miles or 8 minutes
3.Hampton Inn
486 Bradley Boulevard
Richland, WA 99352
Phone No.: 509.943.4400
Fax No.: 509.943.1797
5.67 miles or 12 minutes
4. Red Lion Hotel Richland Hanford House
http://redlion.rdln.com/HotelLocator/HotelOverview.aspx?metaID=40
802 George Washington Way
Richland, WA 99352
Phone No.: 509.946.7611
Fax No.: 509.943.8564
4.99 miles or 11 minutes
5.Courtyard Richland Columbia Point
http://www.marriott.com/hotels/travel/psccy-courtyard-richland-columbia-point/
480 Columbia Point Drive
Richland, WA 99352
Phone No.: 509.942.9400
Fax No.: 509.942.9401
6.7 miles or 13 minutes
January 30, 2012